Research Database

60 results for "Chronic Disease"

Association Between Physical Activity and Inflammatory Markers Among U.S. Adults with Chronic Obstructive Pulmonary Disease

  • Published on Dec. 20, 2013

Purpose: Chronic obstructive pulmonary disease (COPD) may cause not only inflammation in the lungs but also systemic effects. One potential strategy to reduce systemic inflammation and attenuate disease progression is physical activity (PA). However, no nationally representative studies, to our knowledge, have examined the association between objectively measured physical activity ...


Treatment options for type 2 diabetes in adolescents and youth: a study of the comparative efficacy of metformin alone or in combination with rosiglitazone or lifestyle intervention in adolescents with type 2 diabetes

  • Published on April 8, 2007

Abstract: Despite the increased prevalence of type 2 diabetes mellitus (T2DM) in the pediatric population, there is limited information about the relative effectiveness of treatment approaches. This article describes the rationale and design of a National Institutes of Health-sponsored multi-site, randomized, parallel group clinical trial designed to test the hypothesis ...


Validity of physical activity monitors during daily life in patients with COPD

  • Published on Nov. 1, 2013

Background: Symptoms during physical activity and physical inactivity are hallmarks of chronic obstructive pulmonary disease (COPD). Our aim was to evaluate the validity and usability of six activity monitors in patients with COPD against the doubly labelled water (DLW) indirect calorimetry method. Methods: 80 COPD patients (mean±SD age 68±6 years and ...


Reallocating time to sleep, sedentary behaviors, or active behaviors: associations with cardiovascular disease risk biomarkers, NHANES 2005-2006.

  • Published on Jan. 17, 2014

Abstract: Sleep and sedentary and active behaviors are linked to cardiovascular disease risk biomarkers, and across a 24-hour day, increasing time in 1 behavior requires decreasing time in another. We explored associations of reallocating time to sleep, sedentary behavior, or active behaviors with biomarkers. Data (n = 2,185 full sample; n = 923 fasting subanalyses) ...


Reliability and validity of the multimedia activity recall in children and adults (MARCA) in people with chronic obstructive pulmonary disease.

  • Published on Nov. 27, 2013

Objective: To determine the reliability and validity of the Multimedia Activity Recall for Children and Adults (MARCA) in people with chronic obstructive pulmonary disease (COPD). Design: People with COPD and their carers completed the Multimedia Activity Recall for Children and Adults (MARCA) for four, 24-hour periods (including test-retest of 2 days) ...


Relationship between objectively measured physical activity and cardiovascular aging in the general population – The EVIDENT trial

  • Published on Jan. 24, 2014

Background Aging has been associated with an increase in arterial stiffness. We analyzed the relationship between regular physical activity and cardiovascular aging evaluated by the radial augmentation index (rAIx), ambulatory arterial stiffness index (AASI), pulse pressure (PP) and heart age in subjects without atherosclerotic disease. Methods A cross-sectional study was ...


Study to Evaluate the Impact of the “PROactive Telecoaching Program” on Physical Activity in Patients With COPD.

  • Added on March 10, 2014

Sponsor: Novartis Pharmaceuticals Collaborators: Innovative Medicines Initiative (PROactive Project), Innovative Medicines Initiative. Information provided by (Responsible Party): Novartis (Novartis Pharmaceuticals) Clinicaltrials.gov Identifier: NCT01992081 Purpose: This study will test two instruments to measure physical activity in COPD patients: A questionnaire and two small physical activity monitors .Patients will be randomized ...


Accelerometry-measured physical activity and inflammation after gestational diabetes

  • Published on July 2013

Purpose Gestational diabetes mellitus (GDM) is associated with adverse metabolic outcomes after delivery. Physical activity practice improves the inflammatory profile; however, whether this association exists in women with prior GDM remains unknown. Our objective was to examine the cardiometabolic and inflammatory risk factors associated with accelerometer-based measures of physical activity ...



Comparison of Pedometer and Accelerometer Derived Steps in Elderly Individuals With Parkinson’s Disease or Osteoporosis Under Free-Living Conditions.

  • Published on Dec. 4, 2013

Aim To compare self-reported pedometer steps with accelerometer steps under free-living conditions in individuals with Parkinson's disease (PD) or osteoporosis (OP). Methods Seventy-three individuals with PD and 71 individuals with OP wore a pedometer (Yamax LS2000) and an accelerometer (Actigraph GT1M/GT3X+) simultaneously for one week. Results Fifty-one individuals ...