Research Database

48 results for "Diabetes"

The potential cardio-metabolic benefits of replacing time in less-for more-active behaviors in adults with type 2 diabetes

  • Presented on May 21, 2014

Purpose: To examine the cross-sectional associations of objectively derived physical activity and sedentary time with cardiometabolic biomarkers, including the potential collective impact of shifting time use from less towards more active behaviors. Methods: Overweight/obese and/or physically inactive adults with type 2 diabetes (n=294; mean age = 58.0 [SD 8.5] years) wore Actigraph ...


Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

  • Added on June 18, 2014

Detailed Description This lifestyle intervention condition will be compared to a usual care (UC) condition. The aim of this study is to 1) develop a protocol-based, promotora-led lifestyle intervention (PLI) to promote weight loss in at-risk Latinas, and assess its feasibility, and 2) compare changes in weight and cardiometabolic markers—hemoglobin A1...


Estudio Parto: postpartum diabetes prevention program for hispanic women with abnormal glucose tolerance in pregnancy: a randomised controlled trial – study protocol

  • Published on March 10, 2014

Background: Diabetes and obesity have reached epidemic proportions in the U.S. with rates consistently higher among Hispanics as compared to non-Hispanic whites. Among Hispanic women diagnosed with gestational diabetes mellitus (GDM), 50% will go on to develop type 2 diabetes within 5 years of the index pregnancy. Although randomised controlled trials among ...


A personalized approach to exercise promotion in adolescents with type 1 diabetes.

  • Published on Dec. 8, 2009

Purpose: This exploratory study tested the feasibility of conducting a novel, personalized exercise intervention based upon the current fitness levels of adolescents with type 1 diabetes (T1DM). The relationships of perceptions of benefits and barriers to exercise, exercise self-efficacy and family support to exercise adherence and changes in cardiovascular (CV) ...



Treatment options for type 2 diabetes in adolescents and youth: a study of the comparative efficacy of metformin alone or in combination with rosiglitazone or lifestyle intervention in adolescents with type 2 diabetes

  • Published on April 8, 2007

Abstract: Despite the increased prevalence of type 2 diabetes mellitus (T2DM) in the pediatric population, there is limited information about the relative effectiveness of treatment approaches. This article describes the rationale and design of a National Institutes of Health-sponsored multi-site, randomized, parallel group clinical trial designed to test the hypothesis ...


Waist circumference and cardiorespiratory fitness are independently associated with glucose tolerance and insulin resistance in obese women

  • Published on Dec. 12, 2013

Abstract: The purpose of this study was to determine the independent associations between physical activity (PA), cardiorespiratory fitness (CRF), abdominal obesity and insulin action in obese women. We studied 141 abdominally obese women (waist circumference (WC): 106.4 ± 10.2 cm). PA duration (min/day) and intensity (counts/min) were obtained by accelerometry. CRF was ...


Accelerometry-measured physical activity and inflammation after gestational diabetes

  • Published on July 2013

Purpose Gestational diabetes mellitus (GDM) is associated with adverse metabolic outcomes after delivery. Physical activity practice improves the inflammatory profile; however, whether this association exists in women with prior GDM remains unknown. Our objective was to examine the cardiometabolic and inflammatory risk factors associated with accelerometer-based measures of physical activity ...


Sedentary time and markers of chronic low-grade inflammation in a high risk population

  • Published on Oct. 29, 2013

Background Sedentary behaviour has been identified as a distinct risk factor for several health outcomes. Nevertheless, little research has been conducted into the underlying mechanisms driving these observations. This study aimed to investigate the association of objectively measured sedentary time and breaks in sedentary time with markers of chronic low-grade ...


Insulin secretion and its association with physical activity, fitness and screen time in children

  • Published on Oct. 16, 2013

Objective To determine the independent associations of moderate to vigorous physical activity (MVPA), fitness, screen time, and adiposity with insulin secretion in children. Design and Methods Caucasian youth (n = 423/630), 8-10 years old, with at least one obese biological parent, were studied (QUALITY cohort). Insulin secretion was measured using HOMA2-%...