Research Database

124 results for "Elderly"

Skeletal muscle LINE-1 ORF1 mRNA is higher in older humans but decreases with endurance exercise and is negatively associated with higher physical activity

  • Published on August 1, 2019

Abstract The long interspersed nuclear element-1 (L1) is a retrotransposon that constitutes 17% of the human genome and is associated with various diseases and aging. Estimates suggest that ~100 L1 copies are capable of copying and pasting into other regions of the genome. Herein, we examined if skeletal muscle L1 markers are ...



Neuromuscular function of the plantar flexors and predictors of peak power in middle-aged and older males

  • Published on July 30, 2019

Abstract Little evidence exists regarding the contribution of torque and velocity to the age-related decrease in peak power (PP) for the plantar flexors (PFs). A comprehensive assessment of PF neuromuscular function is necessary to elucidate age-related changes, especially between middle-aged and older adults, in order to identify early, age-related decrements. ...


Feasibility Trial Evaluation of a Peer Volunteering Active Aging Intervention

  • Published on July 16, 2019

Background ACE (Active, Connected, Engaged) is a theory-informed, pragmatic intervention using peer volunteering support to promote active ageing in socially disengaged, inactive older adults. This study aimed to establish ACE’s feasibility and acceptability. Methods Fifty-four older adults were recruited as either peer volunteers (activators; n = 15) or participants (ACEs; n = 39). ...


Effects of two web-based interventions promoting physical activity among older adults compared to a delayed intervention control group in Northwestern Germany: Results of the PROMOTE community-based intervention trial

  • Published on July 17, 2019

Abstract Regular physical activity (PA) is of central importance for healthy ageing. However, in Germany, only 42% of older adults currently reach the PA recommendations of the World Health Organization. The aim of this study was to examine the effects of two web-based interventions on PA in adults aged 65–75 years living ...


Translating a “Stand Up and Move More” intervention by state aging units to older adults in underserved communities

  • Published on July 9, 2019

Introduction As aging is associated with functional decline, preventing functional limitations and maintaining independence throughout later life has emerged as an important public health goal. Research indicates that sedentary behavior (prolonged sitting) is associated with functional loss and diminished ability to carry out activities of daily living. Despite many efforts ...




Cognitive Functioning as a Moderator in the Relationship Between the Perceived Neighborhood Physical Environment and Physical Activity in Belgian Older Adults

  • Published on May 4, 2019

Objective To investigate whether the relationship of neighborhood environmental factors with physical activity (PA) is moderated by cognitive functioning in Belgian older adults. Methods Seventy-one older adults completed validated questionnaires on PA and environmental perceptions, wore an accelerometer, and completed a computerized assessment of cognitive functioning. Moderated linear regression analyses ...


Physical Activity and Sedentary Behavior at the End of the Human Lifespan

  • Published on May 4, 2019

Abstract To objectively assess physical activity levels and sedentary behavior in a cohort of Spanish centenarians and their nonagenarian peers. Physical activity and sedentary behavior patterns were objectively measured by an ActiGraph GT3X accelerometer in centenarians (n = 18; 83% women; 100.8 ± 0.8 [100–103] years) and nonagenarians (n = 11; 91% women; 93.3 ± 2.5 [90–98] years). Centenarians showed less counts per ...