Research Database

Classification and Processing of 24-Hour Wrist Accelerometer Data

  • Published on 2017

Background: An important step in accelerometer data analysis is the classification of continuous, 24-hour data into sleep, wake, and non-wear time. We compared classification times and physical activity metrics across different data processing and classification methods. Methods: Participants (n = 576) from the Finnish Retirement and Aging Study (FIREA) wore an accelerometer ...



Actigraphy assessment of sleep quality among patients with acute myeloid leukaemia during induction chemotherapy

  • Published on Apr 2018

Objectives: Patients receiving induction chemotherapy for acute myeloid leukaemia (AML) anecdotally describe poor sleep, but sleep disturbances have not been well-characterised in this population. We aimed to test the feasibility of measuring sleep quality in AML inpatients using a wearable actigraphy device. Methods: Using the ActiGraph GT3X ‘watch’, we ...



Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial

  • Published on Sep 2017

Objective: The objective of this study was to evaluate the efficacy and safety of acupuncture treatment for primary insomnia. Methods: We conducted a single-center, single-blinded, and randomized controlled clinical trial. Seventy-two patients with primary insomnia were randomly assigned into two groups – the acupuncture group, who received acupuncture treatment, and the ...


The relations between sleep, time of physical activity, and time outdoors among adult women

  • Published on Sep 6, 2017

Physical activity and time spent outdoors may be important non-pharmacological approaches to improve sleep quality and duration (or sleep patterns) but there is little empirical research evaluating the two simultaneously. The current study assesses the role of physical activity and time outdoors in predicting sleep health by using objective measurement ...


Sleep duration as a mediator between an alternating day and night shift work schedule and metabolic syndrome among female hospital employees.

  • Published on Feb 2018

Objectives: The main objective was to determine whether sleep duration on work shifts mediates the relationship between a current alternating day and night shift work schedule and metabolic syndrome among female hospital employees. The secondary objective was to assess whether cumulative lifetime shift work exposure was associated with metabolic syndrome. ...


A Pilot Study to Determine the Consistency of Simultaneous Sleep Actigraphy Measurements Comparing All Four Limbs of Patients with Parkinson Disease

  • Published on December 27, 2017

Abstract: Wrist actigraphy is a form of objective sleep measurement that has gained a central role in sleep research and clinical settings. Guidelines for actigraphy recommend placing the monitor on the non-dominant wrist, however, this potentially will be the most involved limb for someone with Parkinson disease, and so alternative ...


A Pilot Characterization of the Human Chronobiome

  • Published on Dec 07, 2017

Abstract Physiological function, disease expression and drug effects vary by time-of-day. Clock disruption in mice results in cardio-metabolic, immunological and neurological dysfunction; circadian misalignment using forced desynchrony increases cardiovascular risk factors in humans. Here we integrated data from remote sensors, physiological and multi-omics analyses to assess the feasibility of detecting ...


Statistical modeling of circadian rhythms of physical activity

  • Published on Jun 21, 2017

Purpose: The proposed symposium will introduce novel and intuitive statistical methods for modeling the human circadian rhythm based on data collected using body-worn physical activity monitors. All methods are motivated by and applied to large observational studies. Rationale: Biological rhythms have been under intense methodological development across all disciplines of ...