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September 21, 2022

Operationalizing Digital Health Technologies: Successes and Failures in Clinical Research

Clinical trial sponsors are increasingly leveraging digital health technologies (DHTs) to capture real-world, patient-centric outcome measures in their studies. Although these tools provide near endless opportunities to improve study efficiencies and unlock new participant insights, many study teams struggle with the operational complexities of deploying DHTs into large-scale, global clinical ...

March 28, 2022

Exploring the Role of Wearable Biosensors Within the DCT Ecosystem

Technology-enabled decentralized clinical trials (DCTs) are transforming drug development by lowering participation barriers and burdens while expanding the opportunities to collect data. However, the operational complexities of managing multiple remote technologies can be overwhelming.

February 25, 2022

Product Updates: CentrePoint® Insight Watch 2.0, Platform Enhancements, and Improved Digital Measures

In 2018, ActiGraph released the CentrePoint® Insight Watch (CPIW), a fit-for-purpose wearable designed to collect continuous, real-world physical activity data - passively, comfortably, and easily - without the need for frequent battery charging. In April of this year, we will release v. 2.0 of that product, which includes a scratch resistant glass ...

August 11, 2021

Oncology Research and Care: Reimagining Digital Innovation

Wearable sensors and connected digital technologies have the potential to revolutionize how we study, treat, and manage cancer research and care. The collection of continuous, real-world physiological and behavioral signals provides an opportunity for oncology researchers to develop a new class of objective and sensitive endpoints that are clinically meaningful ...

April 7, 2021

Navigating The Journey Towards “Future-Proof” Clinical Data Assets

As the digital transformation of clinical research and the adoption of decentralized clinical trials continue to gain momentum, sponsors are increasingly using wearable motion-sensing technologies to capture real-world digital biomarker data. In exchange for the valuable insights into treatment efficacy and quality of life they provide, successful wearable technology deployments ...

March 2, 2021

Wearable Data Gone Awry: Cautionary Tales from the Clinical Research Trenches

Wearable technologies deliver valuable clinical insights, and they also introduce new layers of complexity and risk for study design and clinical operations teams. Selecting a wearable technology that is well-aligned with your study population, endpoints of interest, and trial design is the first step in optimizing the quality of your ...

November 17, 2020

What Level of Evidence is Needed to Evaluate Digital Biomarkers and Measurements?

ActiGraph CEO, Jeremy Wyatt joins a panel of experts from HumanFirst, Atlantic Council, and Samsung NeuroLogica take a deep dive and answer key questions into the evaluation of digital biomarkers and digital measurements during the discussion "What Level of Evidence is Needed to Evaluate Biomarkers and Measurements?”

October 30, 2020

Developing an Effective Data Asset Strategy for Wearable Devices in Clinical Trials

CNS Summit 2020 Spotlight Session, "Developing an Effective Data Asset Strategy for Wearable Devices in Clinical Trials," moderated by Jeremy Wyatt, ActiGraph CEO, and featuring an all-star panel of thought leaders from Bristol Myers Squibb, Takeda, Roche, and the University of California San Diego. Panelists discuss a framework for understanding the ...

September 21, 2020

Traversing the Regulatory Road to Qualifying a Digital Endpoint; Twists and Turns

Mobile in Clinical Trials virtual panel discussion, “Traversing the Regulatory Road to Qualifying a Digital Endpoint; Twists and Turns.” ActiGraph CEO, Jeremy Wyatt, joined a panel of thought leaders from Pfizer, Boehringer Ingelheim, Biogen, and ICON to discuss a framework for the qualification of novel digital endpoints and the regulatory ...

August 20, 2020

Remote Data Capture Strategies to Move Academic Research Forward During a Global Pandemic

The COVID-19 pandemic has created widespread disruptions to nearly every aspect of society. As many universities pivot to virtual instruction and existing studies with traditional workflows grind to a halt amid concerns for the safety of participants and personnel, the impacts of slowing academic research will likely be felt for ...

June 23, 2020

Are Your Wearables Worthy? Bust the myths of ‘validation’ and embrace wearables for your virtual trials

The promise of wearables has always been clear. It’s time to deliver on that promise. COVID-19 and the imminent rise of 5G networks are an accelerant, deepening our commitment to the use of wearables and sensors to capture better digital endpoints remotely. But in our collective rush to run ...

May 28, 2020

Lessons Learned from the Trendsetters in Decentralized Trials: Rapid-Deployment of mHealth Integrations

snapIoT, Covance, and ActiGraph discuss expectations of wearables, achieving successful mHealth integrations, and the industry’s best practices in the rapid deployment of decentralized clinical trials. Topics of discussion: Develop realistic expectations when selecting wearable devices for today’s Decentralized Trials Compare lessons learned from the ‘trendsetters’ in the rapid-deployment ...

January 21, 2020

Selecting and Implementing Mobile Sensors to Collect Clinical Trial Endpoint Data

Today, less than 15% of clinical trials capture data from mobile sensors. In many cases these data are used to derive exploratory endpoints, but in some cases they are being used for primary or secondary endpoints. Mobile sensors can be used to measure aspects of health and function which are difficult ...

May 1, 2019

Developing Validated Digital Clinical Endpoints with Wearable Sensors

In this webinar, ActiGraph’s Jeremy Wyatt is joined by Job Godino, PhD, to discuss key challenges and opportunities around the validation of digital clinical endpoints captured with wearable sensors, addressing both historic data interpretation methods and the ways in which these may change in the future. This 45 minute webinar ...

December 6, 2018

ActiGraph Case Study: How to Plan and Execute a Successful Clinical Trial Wearable Program

ActiGraph experts present a case study outlining essential considerations for the successful implementation of a wearable activity and sleep monitoring program within a clinical trial. In this webinar, we discuss key issues that can derail the assessment and how leveraging the expertise of an experienced partner helps to ensure a ...

September 18, 2018

The Evolving Landscape of Digital Biomarkers & Wearable Sensors

The term “digital biomarkers” is everywhere. New biomarker-focused conferences, journals, and regulatory requirements abound, but it seems like such a broad subject. In this webinar, we discuss the digital biomarker landscape and examine them more specifically in the context of wearables in clinical trials: Why are digital biomarkers important? What ...